| Date | Home | Away | Result |
|---|---|---|---|
| 1/10/26 8:00 AM | Frosinone Calcio | US Catanzaro 1929 | 2-0 |
| 1/10/26 8:00 AM | Virtus Entella | AC Monza | 1-0 |
| 1/10/26 8:00 AM | AC Reggiana 1919 | FC Venice | 1-3 |
| 1/10/26 8:00 AM | FC Südtirol | Spezia Calcio | 2-1 |
| 1/10/26 8:00 AM | US Avellino | Sampdoria Genua | 2-1 |
| 1/10/26 8:00 AM | Carrarese Calcio 1908 | SSC Bari | 1-0 |
| 1/10/26 10:15 AM | Juve Stabia | Pescara Calcio | 2-2 |
| 1/10/26 12:30 PM | FC Cesena | FC Empoli | 0-1 |
| 1/11/26 8:00 AM | Mantova 1911 | Palermo FC | 1-1 |
| 1/11/26 10:15 AM | Padova Calcio | Modena FC | 2-0 |